Worms Hold Key to Prolong Life


Can These Roundworms Hold the Key to Aging?

They maybe wriggly things that look like nothing at all but scientists may have found the anti aging secrets in roundworms.

Biochemist Cynthia Kenyon and her team at the Hillblom Center for the Biology of Aging, have managed to prolong the life of roundworms six-fold by manipulating a gene they share with humans.

Roundworms

roundworms

‘These worms should be dead, a long time ago. But they’re not dead. They’re moving. They’re young.’ says Kenyon.

It all boils down to a gene called the daf-2 gene in the DNA. A gene that explains why some species such as the mayfly can live for one day only and the koi fish can live for 200 years.

The same gene is present in humans and people who live to 100 tend to exhibit mutations to the gene, said Kenyon at the Technology, Entertainment and Design (TED) conference in Edinburgh.

Developments are underway to make take this information to make a drug to prolong our youth. Will 100 be the new 60 years old? Stay tuned.

 

Cynthia Kenyon at the Edinburgh Conference July 2011

Enhanced by Zemanta

A New Anti Aging Power Food : Mushrooms


Mushrooms – The New Power Food

 
The French are obsessed with their mushrooms.

When it is ‘mushroom season’, there are undercover outings in the dark of the night, or at the crack of dawn to find the biggest and the best wild mushrooms.

Lingzhi or Reishi

Lingzhi or Reishi Mushroom

Once you find a spot, it is a super closely guarded secret that you don’t even share with family members. well, maybe on your death bed but even then…

The Chinese are also very keen on their mushrooms. For the longest time they have always known the health benefits of various types of mushrooms and the highest prized ones can go for thousands of dollars for a handful.

The Lingzhi or Reishi Cracked Spores comes to mind

For the Chinese and Japanese and many Far Eastern countries, cooking with mushrooms is an art. There is a mushroom to make every dish a special one, or to have specific meanings. They can also signify the arrival of certain seasons or an impending festival.

In America, 900 million pound of mushrooms are consumed each year, but only 5 % of those mushrooms are not button mushrooms (which is a shame really).

The Mushroom Expert

Steve Farrar has a master degree in Horticulture from Washington State University and he has been studying mushrooms for thirty years. The last ten years, he has been concentrating on the medicinal or health benefits of various mushrooms on our health:

“I’m continually humbled by my ignorance of what’s going on in this incredible complex world of fungi,” Farrar says. “It’s just mind boggling. Even with the well-studied species, nearly every week they’re finding a new bioactive component… Maybe it’s a polysaccharide, maybe it’s an enzyme, a protein, an antioxidant. They are continually finding new things that have profound effects when we consume them as a food or as a dietary supplement.”

Mushrooms have great antioxidant properties and is known to boost the immune system. Aside from the more common antioxidant properties like selenium and polyphenols, mushrooms has this ‘master antioxidant’ ergothioneine which has only recently been generating interest in the health industry even though it was discovered in 1909.

Ergothioneine – ‘Master Antioxidant’

According to Nature journal in 2009, ergothioneine has “an unusual sulfur-containing derivative of the amino acid, histidine,” and can very specifically target DNA oxidative damage.

Steve Farrar also believes that glyconutrients (complex sugars) contained in the fruit body and the mycelia also has many immune benefits:

“The vital information that can be contained in these sugars is astounding,” he says. “…The way they communicate is… through receptor sites on your cells. It’s described as a lock and a key. There are receptor sites depending on the physical structure of the polysaccharides, the side branches, and the substitutions on it, [and] they will lock on to certain components of your immune system and activate it much like they would be activated by coming into contact with the bacteria.

It’s very profound effects, and we don’t fully understand them… But it’s really these long chained polysaccharides (that are immense complex structures), a lot of times bound with proteins or amino acids or different side chains, that have the effect on your immune system.”

The trick is to eat a wide variety of mushrooms (make sure they are organic if possible) across board: oyster mushrooms, shiitake, maitake, brown beech and more. The larger the variety, the better it will be for your immune system.

Or you could take supplements in pill or powder form but make sure it of the highest quality.

 

Watch the interview here with Steve Farrar


Read the original interview and article here with Dr Mercola

 

Enhanced by Zemanta

Will Old Age be a Thing of the Past?


Getting Rid of Old Aging Cells

It seems the Mayo clinic may have come across a way to help us age better, slower and healthier.

It is not going to revert us back to age twenty, but the signs are there that it will help get rid of the old aging cells in our body that is also the main contributors to diseases such as heart disease and arthritis.

old age

Getting Rid of Old Aging Cells

So what are these cells?

“Senescent cells accumulate in various tissues and organs with ageing and have been hypothesized to disrupt tissue structure and function because of the components they secrete” according to Nature – the International Weekly Journal of Science.

By conducting research and experiments on removing senescent cells from our bodies, especially at an older age, researchers and scientists were able to find data to “indicate that cellular senescence is causally implicated in generating age-related phenotypes and that removal of senescent cells can prevent or delay tissue dysfunction and extend healthspan.”

According to Dr. James Kirkland of the Mayo Clinic and co-author of the study:

“By attacking these cells and what they produce, one day we may be able to break the link between aging mechanisms and predisposition to diseases like heart disease, stroke, cancers and dementia.”

Science News puts it this way:

“When a cell’s DNA becomes damaged by things like ultraviolet radiation or toxins, the cell will often enter a senescent state as a precautionary measure against the cancerous growth that can result from such damage. The immune system normally clears dormant cells from tissues. But as an organism ages, its tiring immune system begins to falter in the fight against these cellular zombies. As a consequence, senescent cells begin to accumulate in the older body, gaining strength in numbers.”

And it works if you are already inflicted with age related problems.

“Therapeutic interventions to get rid of senescent cells or block their effects may represent an avenue to make us feel more vital, healthier, and allow us to stay independent for a much longer time,” the Mayo Clinic’s Dr. Jan van Deursen, a study co-author, said in the statement.

So should we all be rushing out to get rid of these cells?

Like all studies, it should be approached with caution as it is still early stages yet. Watch the short video below:

 

 

 

Enhanced by Zemanta